Mark Poznansky raises the issue with his co-authors, of whether to give a third booster shot of a covid vaccine against the threat of the Delta variant and discusses the risks and benefits of balancing scientific understanding on safety with humane decisions on global equity.

“The unvaccinated may ask whether they should now get vaccinated to protect themselves and their families. Meanwhile, some who have been vaccinated wonder whether a booster shot is in order, sooner rather than later, especially given the rise in the delta variant. The answer is not yet clear. Data from Israel, the U.S. and elsewhere suggest that the current COVID-19 vaccines offer less protection against the delta variant than earlier versions of the virus. Early reports from Pfizer support the effectiveness of a booster shot against the delta variant while a review of safety data is pending. In the meantime, we must avoid jeopardizing the effectiveness of the first vaccine doses against original variants as well as the delta variant. The timing and efforts become a balancing act. What has been glaringly clear throughout the pandemic is the need to trust and follow the science in real-time. That means, in part, don’t jump the gun and make assumptions. Yet, it also means making the most informed public health decisions possible at any given moment.”

co -written by Mark C. Poznansky, MD, PhD, Marc Seigel, MD and Jacqueline A. Hart, MD.  

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