Sîrbulescu Lab
Mission Statement:
Research Focus:
VIC Projects List
- Traumatic Brain Injury (TBI): B cell immunotherapy for contusion traumatic brain injury, Immunomodulatory interactions of B cells in neurotrauma
- Amyotrophic Lateral Sclerosis (ALS): Immunomodulatory systemic B cell therapy for ALS, Immune profiling in patients with slow- and rapid-progression of ALS
- Intracerebral Hemorrhage (ICH): Immunophenotyping and immunomodulatory B cell therapy for intracerebral hemorrhage
- Acute Respiratory Distress Syndrome (ARDS): Systemic B cell immunotherapy for hyperoxia induced ARDS
- Wound Healing: B cell immunotherapy for acute and chronic wound healing, Mechanisms of B cell action in the context of wound healing, Novel anti-bacterial therapeutics for chronic diabetic ulcers, CXCL12 as an immunomodulatory therapeutic in wound healing
- Multi-modal mass spectrometry-based imaging: Mass spectrometry imaging and imaging mass cytometry for improving diagnosis, prognosis and biomarker discovery based on clinical tissue biopsies
Highlighted Publications
B cell treatment promotes a neuroprotective microenvironment after traumatic brain injury through reciprocal immunomodulation with infiltrating peripheral myeloid cells.
![VIC Group Photos 2023 DSC07110](https://advancingcures.org/wp-content/uploads/2023/08/VIC-Group-Photos-2023-DSC07110.jpg)
![20230709_164141](https://advancingcures.org/wp-content/uploads/2023/07/20230709_164141.jpg)
![Vic Sirbulescu Group Photos 202320220831_142433](https://advancingcures.org/wp-content/uploads/2023/02/Vic-Sirbulescu-Group-Photos-202320220831_142433.jpg)
![Vic Sirbulescu Group Photos 202320220831_143359](https://advancingcures.org/wp-content/uploads/2023/02/Vic-Sirbulescu-Group-Photos-202320220831_143359.jpg)
![Vic Sirbulescu Group Photos 202320230125_134936](https://advancingcures.org/wp-content/uploads/2023/02/Vic-Sirbulescu-Group-Photos-202320230125_134936.jpg)
![VIC 2021 DSC07650](https://advancingcures.org/wp-content/uploads/2021/11/VIC-2021-DSC07650.jpg)
![VIC-2021-SL-Casual](https://advancingcures.org/wp-content/uploads/2021/11/VIC-2021-SL-Casual.jpg)
Research Team
Liam Dwyer, BS
Rommi Kashlan, BS
Yueyue Xiong, BS
David Verrill, MSc
Saumya Maheshwari, MSc
James Aspden, BSc, MSc
Matthew Murphy, BSc
2015-2018 – Chloe K. Boehm, BS. Research Associate at The Broad Institute of Harvard and MIT
2016 – Erin P.Y. Soon, BS. Graduate Student at Stanford University
2016-2017 – Benjamin Maxner, BS. MD Candidate, University of Massachusetts Medical School
2017 – Akshay Mamidi, BS. Process Engineer at Abbott Laboratories, Singapore
2017-2018 – Gabriela Funez-dePagnier, BS. Research Assistant at Weill Cornell Medical College
2017 – Anders Erickson, BSc. MD Candidate, Toronto University Medical School, Canada
2017 – Claire S.Y. Chan, B.Sc. Undergraduate Student, Imperial College London, UK
2017 – William Porter Undergraduate Student
2018 – Dominique Kiki Carey, BS. Teaching Assistant at University of Massachusetts Amherst
2018 – Petra Paisz, BS. MD/PhD Candidate, Imperial College London, UK
2019 – Orla Mostyn Williams, MSc. MD Candidate, Imperial College London, UK
2020 – Emily Hill, BA – Undergraduate Student, summer intern
2019-2020 – Gina Jin, B. Sc. – Research Technician I
2019-2020 – Michael H. Chapin, B. Sc. – Lab Manager & Research Associate
2018-2021 – Joshua M. Hess, B. Sc. – Research Associate
2020 – 2021 – Kento Kawai, PhD – Research Fellow
2021 – Shannon Gallup,BS – Undergraduate Student Intern
2021 – Kyle Mickelson – Undergraduate Student Intern
2021 – Jinghao Wang – Undergraduate Student Intern
2022 – Sarah Huang – Undergraduate Student Intern
2022 – Rigneyla Akhotsang – Undergraduate Student Intern