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Shibani S. Mukerji, M.D., Ph.D

Principal Investigator

Dr. Mukerji received specialized clinical training in the neurological management of infectious diseases from the Mass General Brigham residency and fellowship programs and sees patients with neurological complications from infectious diseases in the MGH Neurology Department and the Division of Infectious Diseases. Dr. Mukerji completed a postdoctoral fellowship in neurovirology with Dr. Dana Gabuzda at the Dana Farber Cancer Center. She has a strong record of transdisciplinary collaborative efforts and has research expertise in molecular neuroscience, computational modeling, and patient- oriented research and is dedicated to improving the cognitive and mental health of people with HIV and emerging infections. She is the recipient of the NIMH K23 Fellowship Grant, Center for AIDS Research Developmental Award, the HMS Eleanor and Miles Shore Award and is the 2021-2022 Rappaport Fellow.

Dr. Mukerji grew up in Phoenix and enjoys spending time biking and traveling with her husband and daughter.

Prior Experience

Dr. Mukerji’s predoctoral work focused on preclinical models investigating activin A as an early endogenous response required for neuronal survival during oxidative challenge to hypoxia and ischemia. Following residency, she received a master’s degree in clinical research investigation and has since modeled systemic factors that influence cognitive decline, depression and frailty in people with HIV.

She was a co-investigator on the Phase II clinical trial “A Study of the Gut Barrier and Blood Vessel Inflammation in Individuals with and without HIV”. She is the
PI of the MGB Prospective Encephalitis and Meningitis Study, which has contributed to our understanding of viral genomics and neurological complications of emerging infectious diseases including Powassan and Eastern Equine Encephalitis viruses. In 2020, she served as the MGH/BWH site PI for GCS-COVID-19 consortium contributing neurological data for over 1800 hospitalized people with COVID-19, and co-authored the landmark paper on neuropathological findings in COVID-19 in the New England Journal of Medicine.

Academic Credentials

Outside of VIC

Dr. Mukerji is a member of the Clinical Research Subcommittee in the American Academy of Neurology and is an Associate Editor for The Neurohospitalist. She serves on the Board of the Healing Our Community Collaborative, a nonprofit organization dedicated to providing HIV health education and prevention programs for women infected with, affected by, or at risk for HIV/AIDS in the Greater Boston area.