User Profile
  • 1996 - 2000 B.S. Biology, Ludong University, Yantai, China
  • 2000 - 2003 M.S. Biochemistry and Molecular Biology, Guangdong Medical University, Zhanjiang, China
  • 2004 - 2005 Instructor, Guangdong Medical University, Zhanjiang, China
  • 2005 - 2010 Ph.D. Medicine, Wuhan University, Wuhan, China
  • 2007 - 2009 Visiting Research Scholar, Massachusetts General Hospital, Boston, MA
  • 2010 - 2013 Postdoctoral Research Fellow, Fudan University, Shanghai, China
  • 2013 - 2015 Research associate, Fudan University, Shanghai, China
  • 2015 - 2016 Postdoctoral Research Fellow, University of Pittsburgh, Pittsburgh, PA
  • 2017 - Present Research fellow in VIC, MGH, Harvard medical school
  1. Deng J*, Qu X*, Lu P, Yang X, Zhu Y, Ji H, Wang Y, Jiang Z, Li X, Zhong Y, Yang H, Pan H, Young W, Zhu H. (2017). Molecular therapy nucleic acids [Paper #2016MTNA000374R]
  2. Wang P*, Qu X*, Zhou X, Shen Y, Ji H, Fu Z, Deng J, Lu P, Yu W, Lu H, Zhu H. Two cellular microRNAs, miR-196b and miR-1290, contribute to HIV-1 latency. (2015). Virology, 486, 228-238.
  3. Qu X, Wang P, Ding D, Wang X, Zhang G, Zhou X, Liu L, Zhu X, Zeng H, Zhu H. Zinc Finger Nuclease: a new approach for excising HIV-1 proviral DNA from infected human T cells. (2014). Mol Biol Rep, 41, 5819-5827.
  4. Qu X, Wang P, Ding D, Li L, Wang H, Ma L, Zhou X, Liu S, Wang X, Zhang G, Liu S, Liu L, Wang J, Zhang F, Lu D, Zhu H. Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells. (2013). Nucl Acids Res, 41, 7771-7782.
  5. Qu X, Ying H, Wang X, Kong C, Zhou X, Wang P, Zhu H. Histone deacetylase inhibitor MC1293 induces latent HIV-1 reactivation by histone modification in vitro latency cell lines. (2013). Curr HIV Res, 11, 24-29.
  6. Qu X, Zhou X, Zhou K, Xie X, Tian Y.New mutation in the MYOC gene and its association with primary open-angle glaucoma in a Chinese family. (2010). Mol Biol Rep, 37, 255-261.
  7. Lu P, Qu X, Shen Y, Jiang Z, Wang P, Zeng H, Ji H, Deng J, Yang X, Li X, Lu H, Zhu H. The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb. (2016). Science Reports, 6, 24100.
  8. Wang P, Qu X, Wang X, Liu L, Zhu X, Zeng H, Zhu H. Specific Reactivation of Latent HIV-1 with Designer Zinc-Finger Transcription Factors Targeting the HIV-1 5’ LTR Promoter. (2014). Gene Therapy, 21, 490-495.
  9. Wang P, Qu X, Wang X, Liu L, Zhu X, Zeng H, Zhu H. As2O3 synergistically reactivate latent HIV-1 by induction of NF-κB. (2013). Antiviral Research, 100, 688-697.
  10. Ding D, Qu X, Li L, Zhou X, Liu S, Lin S, Wang P, Liu S, Kong C, Wang X, Liu L, Zhu H. Involvement of histone methyltransferase GLP in HIV-1 latency through catalysis of H3K9 dimethylation. (2013). Virology, 440, 182-189.
  11. He C, Qu X, Wan J, Rong R, Huang L, Cai C, Zhou K, Gu Y, Qian SY, Kang JX. Inhibiting delta-6 desaturase activity suppresses tumor growth in mice. (2012). PLoS One, 7, e47567.
  12. He C, Qu X, Cui L, Wang J, Kang JX. Improved spatial learning performance of fat-1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexaenoic acid. (2009). Proc Natl Acad Sci USA, 106, 11370-11375.
  13. Xie X, Zhou X, Qu X, Wen J, Tian Y, Zheng F. Two novel myocilin mutations in a Chinese family with primary open-angle glaucoma. (2008). Mol Vis, 14, 1666-1672.
  14. Zhu X, Liu S, Wang P, Qu X, Wang X, Zeng H, Chen H, Zhu H. Oxaliplatin antagonizes HIV-1 latency by activating NF-kB without causing global T cell activation. (2014). Biochem Biophys Res Commun, 450, 202-207.
  15. Zeng H, Liu S, Wang P, Qu X, Ji H, Wang X, Zhu X, Song Z, Yang X, Ma Z, Zhu H. Dilazep synergistically reactivates latent HIV-1 in latently infected cells. (2014). Mol Biol Rep, 41, 7697-7704.
  16. Ying H, Zhang Y, Zhou X, Qu X, Wang P, Liu S, Lu D, Zhu H. Selective Histonedeacetylase Inhibitor M344 Intervenes in HIV-1 Latency through Increasing Histone Acetylation and Activation of NF-kappaB. (2012). PLoS One, 7, e48832.
  17. Wang X, Wang P, Fu Z, Ji H, Qu X, Zeng H, Zhu X, Deng J, Lu P, Zha S, Song Z, Zhu H. Designed transcription activator-like effector proteins efficiently induced the expression of latent HIV-1 in latently infected cells. (2015). AIDS Res Hum Retroviruses, 31, 98-106.
  18. Pender-Cudlip MC, Krag KJ, Martini D, Yu J, Guidi A, Skinner SS, Zhang Y, Qu X, He C, Xu Y, Qian SY, Kang JX. Delta-6-desaturase activity and arachidonic acid synthesis are increased in human breast cancer tissue. (2013). Cancer Sci, 104, 760-764.
  19. Ji H, Jiang Z, Lu P, Ma L, Li C, Pan H, Fu Z, Qu X, Wang P, Deng J, Yang X, Wang J, Zhu H. Specific reactivation of latent HIV-1 by dCas9-SunTag-VP64-mediated guide RNA targeting the HIV-1 promoter. (2016). Molecular Therapy, 24, 508-521.
  20. Cai C, Zhou X, Zhao L, Yao X, Tu J, Zheng F, Qu X. Optical detection of plasma chitotriosidase activity in heal thy Chinese children using fluorescence spectrophotometry. (2007) Clin Chinm Acta, 379, 134-138.
  • Immunotherapy of ovarian cancer, neck and head tumors.
  • Immune profiling of Aperisys project by mass cytometry (CyTOF).