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Semiconductor diode laser device adjuvanting intradermal vaccine

Kimizuka Y, Callahan JJ, Huang Z, Morse K, Katagiri W, Shigeta A, Bronson R, Takeuchi S, Shimaoka Y, Chan MP, Zeng Y, Li B, Chen H, Tan RY, Dwyer C, Mulley T, Leblanc P, Goudie C, Gelfand J, Tsukada K, Brauns T, Poznansky MC, Bean D, Kashiwagi S. Vaccine. 2017 Apr 25;35(18):2404-2412. doi: 10.1016/j.vaccine.2017.03.036. Epub 2017 Mar 30. PMID: 28365253

HELZ2 Is an IFN Effector Mediating Suppression of Dengue Virus.

Fusco DN, Pratt H, Kandilas S, Cheon SS, Lin W, Cronkite DA, Basavappa M, Jeffrey KL, Anselmo A, Sadreyev R, Yapp C, Shi X, O’Sullivan JF, Gerszten RE, Tomaru T, Yoshino S, Satoh T, Chung RT.
Front Microbiol. 2017 Feb 20;8:240. doi: 10.3389/fmicb.2017.00240. eCollection 2017. PMID: 28265266

Biomechanically primed liver microtumor array as a high-throughput mechanopharmacological screening platform for stroma-reprogrammed combinatorial therapy.

Zhu L, Fan X, Wang B, Liu L, Yan X, Zhou L, Zeng Y, Poznansky MC, Wang L, Chen H, Du Y. Biomaterials. 2017 Apr;124:12-24. doi: 10.1016/j.biomaterials.2017.01.030.

Classification of Laser Vaccine Adjuvants.

Kashiwagi S, Brauns T, Poznansky MC. J Vaccines Vaccin. 2016 Feb;7(1). pii: 307.

Improved Antitumoral Efficacy of Mesothelin Targeted Immune Activating Fusion Protein in Murine Model of Ovarian Cancer

Yang Zeng, Binghao Li, Patrick Reeves, Chongzhao Ran, Zhao Liu, Mojgan Agha-Abbaslou, Jianping Yuan, Pierre Leblanc, Ann Sluder, Jeffrey Gelfand, Timothy Brauns, Mark Poznansky and Huabiao Chen. Int J Cancer Clin Res. 2016, 3: 051

A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice.

Sayeed MA, Bufano MK, Xu P, Eckhoff G, Charles RC, Alam MM, Sultana T, Rashu MR, Berger A, Gonzalez-Escobedo G, Mandlik A, Bhuiyan TR, Leung DT, LaRocque RC, Harris JB, Calderwood SB, Qadri F, Vann WF, Kováč P, Ryan ET.
PLoS Negl Trop Dis. 2015 Jul 8;9(7):e0003881. doi: 10.1371/journal.pntd.0003881. eCollection 2015 Jul.

Alginate Encapsulant Incorporating CXCL12 Supports Long‐Term Allo‐and Xenoislet Transplantation Without Systemic Immune Suppression

Chen T, Yuan J, Duncanson S, Hibert ML, Kodish BC, Mylavaganam G, Maker M, Li H, Sremac M, Santuosso M, Forbes B, Kashiwagi S, Cao J, Lei J, Thomas M, Hartono C, Sachs D, Markmann J, Sambanis A, Poznansky MC. Amer J Transplant 2015;15:618-627.

Could mycobacterial Hsp70-containing fusion protein lead the way to an affordable therapeutic cancer vaccine?

Brauns T, Leblanc P, Gelfand JA, Poznanski M.
Expert Rev Vaccines. 2015 Mar;14(3):435-46. doi: 10.1586/14760584.2015.979797. Epub 2014 Dec 13. Review.

Laser vaccine adjuvants: History, progress, and potential

Kashiwagi S, Brauns T, Gelfand J, Poznansky MC. Hum Vaccin Immunother 2014;10(7):1892-907.

A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma

Yuan J, Kashiwagi S, Reeves P, Nezivar J, Yang Y, Arrifin NH, Nguyen M, Jean-Mary G, Tong X, Uppal P, Korochkina S, Forbes B, Chen T, Righi E, Bronson R, Chen H, Orsulic S, Brauns T, Leblanc P, Scholler N, Dranoff G, Gelfand J, Poznansky MC. A novel mycobacterial. J Hematol Oncol 2014 Feb 24;7:15.

Evaluation in mice of a conjugate vaccine for cholera made from Vibrio cholerae O1 (Ogawa) O-specific polysaccharide

Alam MM, Bufano MK, Xu P, Kalsy A, Yu Y, Freeman YW, Sultana T, Rashu MR, Desai I, Eckhoff G, Leung DT, Charles RC, LaRocque RC, Harris JB, Clements JD, Calderwood SB, Qadri F, Vann WF, Kováč P, Ryan ET. PLoS Negl Trop Dis. 2014 Feb 6;8(2):e2683. doi: 10.1371/journal.pntd.0002683. eCollection 2014 Feb.

VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever.

Leblanc P, Moise L, Luza C, Chantaralawan K, Lezeau L, Yuan J, Field M, Richer D, Boyle C, Martin WD, Fishman JB, Berg EA, Baker D, Zeigler B, Mais DE, Taylor W, Coleman R, Warren HS, Gelfand JA, De Groot AS, Brauns T, Poznansky MC. Hum Vaccin Immunother. 2014;10(10):3022-38. doi: 10.4161/hv.34413. Review.

Near-infrared laser adjuvant for influenza vaccine

Kashiwagi S, Yuan J, Forbes B, Hibert ML, Lee EL, Whicher L, Goudie C, Yang Y, Chen T, Edelblute B, Collette B, Edington L, Trussler J, Nezivar J, Leblanc P, Tsukada P, Suematsu M, Dover J, Brauns T, Gelfand J, and Poznansky MC. PLoS One 2013 Dec 11;8(12):e82899.

Near-infrared laser adjuvant for influenza vaccine.

Kashiwagi S, Yuan J, Forbes B, Hibert ML, Lee EL, Whicher L, Goudie C, Yang Y, Chen T, Edelblute B, Collette B, Edington L, Trussler J, Nezivar J, Leblanc P, Bronson R, Tsukada K, Suematsu M, Dover J, Brauns T, Gelfand J, Poznansky MC. PLoS One. 2013 Dec 11;8(12):e82899. doi: 10.1371/journal.pone.0082899.

Accelerated vaccine development against emerging infectious diseases

Leblanc PR, Yuan J, Brauns T, Gelfand JA, Poznansky MC. Hum Vaccin Immunother 2012 Jul;8(7):1010-2.

Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy

Yuhui Huang, Jianping Yuan, Elda Righi, Walid S Kamoun, Marek Ancukiewicz, Jean Nezivar, Michael Santosuosso, John D Martin, Margaret R Martin, Fabrizio Vianello, Pierre Leblanc, Lance L Munn, Peigen Huang, Dan G Duda, Dai Fukumura, Rakesh K Jain, Mark C Poznansky. PNASUS 2012;109(43):17561-6

CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer

Elda Righi, Satoshi Kashiwagi, Jianping Yuan, Michael Santosuosso, Pierre Leblanc, Rachel Ingraham, Benjamin Forbes, Beth Edelblute, Brian Collette, Deyin Xing, Magdalena Kowalski, Maria Cristina Mingari, Fabrizio Vianello, Michael Birrer, Sandra Orsulic, Glenn Dranoff, Mark C Poznansky. Cancer Research 2011 Aug 15;71(16):5522-34.